Soft Tissue and breast cancer

Saturday, October 4, 2008

Soft Tissue, Thrilling Novel on Breast Cancer; $16.00




































A Thrilling Novel on Breast Cancer $16.00

SCALPEL: THE HIV/AIDS NOVEL $27.00

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Soft Tissue by N. A. Akamike, ISBN #: 978-0-8059-8446-0

Soft Tissue: The Unsolved Mystery, Breast Cancer” is a fictitious story that blends aspects of medical and sociological drama creating a contemporary, thrilling, fast paced and engaging novel.
The story begins with Roxy Adams striking a friendship with Elaine, Ifeoma, and Beatrice during the Chicago’s mayoral election. Their friendship culminated in a vacation to Egypt. Roxy, the daughter of an industrialist father whose wife has a genetic link to cancer, fell in love with James Ugo, a scientist, en route to Egypt. A romantic relationship developed between James and Roxy that continued after the end of the Egyptian vacation. Her relationship with James headed towards marriage. The interests and professional ties of Roxy, an attorney, and her friends provided a forum for an extensive discussion of breast cancer. The scientist and medical doctors elaborated on most aspects of the cancer, possible risk factors, including oral contraceptives and hormone based therapies. When Roxy was suddenly diagnosed with breast cancer, her curiosity about the origin and progress of breast cancer expanded the conversation to include considerations of stem cell research and genetic influences. The diagnosis exposed the fragility of the love between Roxy and James. The emotional turmoil as a result of the diagnosis compounded by potential infidelity by James caused Roxy to have an accident. On the other hand, Denise who suffered a stroke as a consequence of HRT use faced uncertainty in her proposed marriage to her long term fiancé, Charles.

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About the Author N. A. Akamike is a research scientist in the areas of industrial chemistry and medicinal chemistry, emphasizing in pharmaceutical sciences. He is a recipient of the Sigma Xi Award (excellence in science), the inventor on four patents related to cancer (World Patent, U.S. Patent, European Patent), and the coauthor of eight scientific publications in the area of cancer and HIV/AIDS. Akamike is a staff scientist in drug discovery with major pharmaceutical companies, including Biotechs in the San Francisco Bay area.

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Available on line:
http://www.authorstream.com/presentation-search/tag/akamike
http://www.amazon.com/
http://www.borders.com/
http://www.redleadbooks.com/
http://www.bookfinder.com/
http://softtissuecancer.mysite.com/
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email: gsofttissue@gmail.com
kusmetique@yahoo.com

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Patents and Publications
Patents:

(1996) Issued: European Patent No. EP705250A1Bis-imide Polycyclic and Heterocyclic Chromophores useful as tumoricidalsAD. Patten, GJ. Pacofsky, SP. Seitz, EA. Akamike, RJ. Cheney, RF. Kaltenbach, MJ. Orwat.

(1996) Issued: U.S. Patent No. 5,585,382Polycyclic and Heteroaromatic Chromophores for bis-imides TumoricidalsAD. Patten, GJ. Pacofsky, SP. Seitz, EA. Akamike, RJ. Cheney, RF. Kaltenbach, MJ. Orwat.

(1995) Issued: World Patent No. WO9500490A1Bis-imide Polycyclic and Heterocyclic Chromophores useful as tumoricidalsAD. Patten, GJ. Pacofsky, SP. Seitz, EA. Akamike, RJ. Cheney, RF. Kaltenbach, MJ. Orwat.

(1995) Issued: U. S. Patent No. 5,416,089Bis-imide Polycyclic and Heteroaromatic Chromophores for Bis-imide tumoricidalsEA. Akamike, RJ. Cheney, RF. Kaltenbach, MJ. Orwat. GJ. Pacofsky, AD. Patten, SP. Seitz

Publications:

Carini, D. J., Kaltenbach, R. F., Liu, J., Benfield, P. A., Boylan, J., Boisclair, M., Brizuela, L., Burton, C. R., Cox, S., Grafstrom, R., Harrison, B.A., Harrison, K., Akamike, E., Markwalder, J. A., Nakano, Y., Seitz, S. P., Sharp, D. M., Trainor, G. L., Sielecki, T. M.,
Identification of Selective Inhibitors of Cyclin Dependent Kinase 4
Bioorganic & Medicinal Chemistry Letters, 2001, vol. 11, No. 2, pages 209-11

Robert J. Cheney, Stephen G. Swartz, Arthur D. Patten, Emeka A. Akamike, Jung-Hui Sun, Robert F. Kaltenbach III, George L. Trainor, Mike Vavala, et. al.
The DuPont Merck Pharmaceutical Co., Wilmington, DE, U. S. A
The Synthesis and Antitumor Evaluation of Unsymmetrical Bis-imides.
Biorganic & Medicinal Chemistry Letters, 1997, vol. 7, No. 2, pages 163-168

De Lucca, George V.; Kim, Ui T.; Akamike, Emeka A.; Lam, Patrick; Clark, Charles; Rodgers, James; Wang, Haisheng; Ko, Soo; Srivastava, Anurug; et.al
The DuPont Merck Pharmaceutical Co., Wilmington, DE U. S. A.
Structure Activity Relationship of Cyclic Ureas With Asymmetric P2/P2' substituents: Potent Inhibitors of HIV-1 Protease
American Chemical Society, Division of Medicinal Chemistry, April 13-17, 1997

Wendell W. Wilkerson, Emeka A. Akamike, Walter W. Cheatham, Dale C. Collins,Andrea Y. Hollis: The DuPont Merck Pharmaceutical Co., Wilmington, DE
HIV Protease Inhibitory Bis-benzamide Cyclic Ureas: A Quantitative Structure-Activity Relationship Analysis,
Journal Of Medicinal Chemistry, 1996, vol. 39, No. 21, pages 4299-4312

Micheal T. Furlong, Hanley N. Abramson, Nnaemeka A. Akamike, and Henry C.Wormser: Approach To Aminated Anthracyclines via Intramolecular MarschalkReaction.;
Synthetic Communications, 20(17), 2691 -2697, (1990)

Abramson, H. N., Akamike, N. A., Banning, J. W., Natchman, J. P., Nagia, Z. M,Wormser, H. C.: Synthesis and Biological Evaluation of Certain 1- and 1,4- substituted Anthraquinones.
The Pharmacologists. (1985), 27, No. 3, 109

Akamike, N. A., Abramson, H. N., Wormser, H. C., Sardessai, M. S.,
A Novel Method For the Displacement of Halogen At The 1-position of Anthraquinones By Acetamides.
American Chemical Society, Division of Organic Chemistry, April 22, 1990

Furlong, M. T., Abramson, H. N., Akamike, N. A., Wormser, H. C.;Synthesis of Aminated Daunomycin Analogs Via Intramolecular Marschalk Reaction
American Chemical Society, Division of Medicinal Chemistry, April 22,1990
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